<span id="v9r9v"><video id="v9r9v"></video></span>
<strike id="v9r9v"><video id="v9r9v"></video></strike>
<th id="v9r9v"></th>
<th id="v9r9v"></th>
<span id="v9r9v"><video id="v9r9v"></video></span>
<progress id="v9r9v"><noframes id="v9r9v"><span id="v9r9v"><noframes id="v9r9v">
您的位置:首頁>>分析化學>>藥物分析標準品>>B8276 BUTYRIC ACID SODIUM 156-54-7
Cat. Number
B8276
Chemical Name
B8276 BUTYRIC ACID SODIUM 156-54-7
CAS Number
156-54-7
Mol. Formula
C4H7NaO2
Mol. Weight
110.09
Qty 1
1g
Qty 2
25g
Appearance
White powder
Application Notes
≥98%
Synonym
Sodium butyrate, Sodium butanoate
Melting Pt.
250-253°C
Solubility
Soluble in water.
Storage condition
Ambient
References

Sodium butyrate is an inhibitor of histone deacetylases (HDACs) that exhibits antidepressant, immunomodulatory, and anticancer activities. In animals undergoing the light dark test, tail suspension test, and forced swim test, sodium butyrate decreases restraint stress-induced depression. In prostate cancer cells, this compound inhibits cell growth, induces apoptosis, downregulates expression of Bcl-xl and Bcl-2, and upregulates expression of Bak and Bax. Additionally, sodium butyrate decreases release of IL-12 and increases production of IL-23 in dendritic cells. Sodium butyrate also alters RNA splicing.


References

Han A, Sung YB, Chung SY, et al. Possible additional antidepressant-like mechanism of sodium butyrate: targeting the hippocampus. Neuropharmacology. 2014 Jun;81:292-302. PMID: 24607816.

Mu D, Gao Z, Guo H, et al. Sodium butyrate induces growth inhibition and apoptosis in human prostate cancer DU145 cells by up-regulation of the expression of annexin A1. PLoS One. 2013 Sep 23;8(9):e74922. PMID: 24086397.

Berndt BE, Zhang M, Owyang SY, et al. Butyrate increases IL-23 production by stimulated dendritic cells. Am J Physiol Gastrointest Liver Physiol. 2012 Dec 15;303(12):G1384-92. PMID: 23086919.

Hnilicová J, Hozeifi S, Du?ková E, et al. Histone deacetylase activity modulates alternative splicing. PLoS One. 2011 Feb 2;6(2):e16727. PMID: 21311748.



下一個:CAMBINOL上一個:BELINOSTAT
在線咨詢 聯系方式 二維碼

服務熱線

021-60498804

掃一掃,關注我們

人妻a∨中文字幕,亚洲AV日韩AV永久无码绿巨人,一国产永久视频,2022一本久道久久综合狂躁,国产欧美日韩在线视频一区 日韩精品Aⅴ无码AV 狠狠久夜一区二区三区 亚洲国产精品无码高潮 精品无码一区二区三在线观看 專業选择!国际品质好吊操视频 中文字幕一区二区人妻本田岬 久久综合电影一区 日韩AV不卡一区二区三区无码 欧美色欧美亚洲日韩在线播放